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* Now accepting applications for Postdoctoral Fellows

* Now accepting applications for Ph.D. rotations (wet and dry research projects)

To apply to the lab, send a cover letter and curriculum vitae to Jill Dowen

Embryonic stem cells grow as round colonies on top of a layer of long fibroblast supporting cells.

Embryonic stem cells grow as round colonies on top of a layer of long fibroblast supporting cells.

 

Gene regulation and chromosome structure during development and disease

Research in the lab investigates the link between genome organization and gene expression. We seek to understand how the looping of DNA impacts the expression of genes within a cell and how dynamic changes are brought about during normal development and disease processes. We use embryonic stem cells, cancer cells, and functional genomics approaches to study the mechanisms of transcriptional regulation and control of chromosome architecture.